1.The apostle Peter encouraged his readers to make a commitment to stand up for Jesus, especially during extreme suffering.
使徒彼得鼓励他的读者，要立定心志来为耶稣做见证，特别在遭受大患难之时。
2.For instance, 1800, 1812, 1821, 1836 and 1856 were years of total crop failure and extreme suffering.
比如说，1800,1812,1821,1836和1856，农作物几乎颗粒无收，生存环境极端恶劣。
3.The guidelines demand that the patient is experiencing extreme suffering
这些指导原则要求，患者须正在经受极度的痛苦，